Guthrie Center, IA is a city located in Guthrie County, Iowa and has a land area of 172.22 square miles (446.05 km2). The water area for the city is 0.05 square miles or 0.13 km2. There is one unique zip code in Guthrie Center, Iowa and it is 50115. The area code(s) for Guthrie Center is 641.
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